Pune University Exam Paper
B.E. (Instrumentation & Control)
ADVANCED BIOMEDICAL INSTRUMENTATION
(2008 Pattern) (Elective – III) (Sem. – II)
Time :3 Hours] [Max. Marks :100
Instructions to the candidates:
1) Answer 3 questions from Section I and 3 questions from Section II.
2) Answers to the two sections should be written in separate books.
3) Neat diagrams must be drawn wherever necessary.
SECTION – I
QI) a) With the help of neat diagram, explain the working of programmable pacemaker. 
b) Draw and explain the heart-lung machine model.
Q2) a) It is required to set up an ICU for 8 beds. Elaborate the implementation plans. 
b) What is a synchronized dc defibrillator? Draw a block diagram of it and explain its working? 
Q3) a) Explain the need and working of an ‘Autoanalyser’. 
b) With the help of graph, explain the basic working principle of a pulse oximeter. [R]
c) Explain the working of an In-Vivo type of oximeter with the help of a suitable diagram. 
Q4) a) Describe with the help of neat waveform various modulation techniques for a typical Telemedicine System. 
b) Explain the conductivity type blood cell counter for RBC and WBC measurement. 
Explain the principle of CT-scanning. How it overcomes the drawback of X-Ray imaging? 
What is the role of ‘Hounsfield number’ in image reconstruction? 
Describe the various components of X-ray machine. 
Draw the diagram of image intensifier and explain how it helps to improve the image qualify in fluoroscopy. 
SECTION – II
With the help of a suitable block diagram, explain the working of Gamma camera. 
Explain A scan, B scan and M-scan in ultrasound imaging. 
Draw a diagram, explaining what is meant by spin-spin relaxation time and spin lattice relaxation time. What is the importance of it? 
Write a note on Positron Emission Tomography. 
What is Nuclear medicine? Describe various types of detectors that are used to detect p and Y rays. 
With the help of a suitable block diagram, explain the working of rectilinear Scanner. 
Explain laser application in diabetic retinopathy and glaucoma.  Explain in brief various types of dialysers used for Hemodialysis. 
Describe various Orthotic and Prosthetic devices. 
Explain different types of wheelchair and joysticks. Specify their materials and properties. 
What is kidney stone? Explain lithotripsy based on acoustic shock wave with plasma explosion. 
Explain Instrumentation in Hemodialysis.