GITAM University Thermodynamics Syllabus
B.Tech. (BT) III Semester
Course Code : EURBT305 Category : BE
Credits: 3 Hours : 3 per week
The first law and other basic concepts: Joule’s experiments – internal energy – The
first law of thermodynamics – thermodynamic state functions – enthalpy – the steady
state – steady flow process – equilibrium – the phase rule – the reversible process –
constant V and constant P processes – Heat capacity.
The second law of thermodynamics: Statement of the second law – heat engines –
thermodynamic temperature scales – thermodynamic temperature and ideal gas scale.
Entropy: entropy changes of an ideal gas – mathematical statement of the second law
– the third law of thermodynamics.
Thermodynamic properties : PVT behavior, Thermodynamic property
relations.Solution thermodynamics : fundamental property relations – chemical
potential and Phase equilibria, fugacity and fugacity coefficient, vapor/liquid
equilibrium for pure species, fugacity of a pure liquid, fugacity and fugacity
coefficient species in solution.
Chemical reaction equilibria: the reaction coordinate – application of equilibrium
criteria to chemical reactions – the standard Gibbs energy change and the equilibrium
constant – effect of temperature on the equilibrium constant – evaluation of
equilibrium constants – relation of equilibrium constants to composition – equilibrium
conversions for single reactions – phase rule and duhem’s theorem for reacting
systems – multireaction equilibria.
Factors affecting stability of double stranded DNA. Statistical thermodynamics of
monomer-dimer equilibrium for DNA and brief discussion of implications for PCR
primer design and DNA microarray design. The helix-coil transition in polypeptides.
Ligand-receptor binding equilibria.
1. Introduction to chemical engineering thermodynamics. J.M.Smith, H.C.Vanness
and M.M.Abbott. 6th Ed. McGraw Hill Book Co., New York., 2001
2. Kinetics and energetics and biotechnology. J.A.Roels. Elsevier. 1983.
3. Chemical, Biochemical and Engineering Thermodynamics 4th Edition, Sandler.
W (2006) Wiley.
4. Physical chemistry: principles and applications in biological sciences. I.Tinoco,
Sauer and Wang. 2007. Dorling Kindersley (India) pvt.ltd.