AIIMS Pharmacology Syllabus

AIIMS Pharmacology Syllabus – Part II





MBBS student, at the end of one and a half years training in Pharmacology, is expected to:

  1. Understand pharmacokinetic and pharmacodynamic principles involved in the use of drugs
  2. Understand and identify the various factors that can affect the action of drugs
  3. Know the various routes of drug administration with advantages and disadvantages of the various routes
  4. Undertake dosage calculations as appropriate for the patient and be able to select the proper drug and dose for the at risk population i.e. patients with kidney or liver disease, elderly, pregnant and lactating females, and children.
  5. Understand the importance of rational prescribing of drugs and the concept of essential drugs
  6. To be able to identify and monitor adverse drug reactions (ADRs) and appreciate the importance of ADR reporting
  7. Know the drugs used in systemic illnesses, infections and chemotherapy etc. with main mechanism(s) of action, pharmacokinetics, uses, side-effects and indications
  8. Understand the principles and practice of pharmacy
  9. Understand the methods in experimental pharmacology, principles of bioassay and be able to correlate drug effects with the action of drugs at the receptors.
  10. Have knowledge of common drugs and doses used for different ailments
  11. Have an understanding of basic mechanism by which a drug acts
  12. Should be able to select rationally from the available drugs

COURSE CONTENT Theory (A)         General Pharmacology

a)      Absorption, distribution, metabolism and elimination of drugs, routes of drug administration

b)       Basic principles of drug action

c)       Adverse reactions to drugs

d)       Factors modifying drug response

(B) Autonomic nervous system & Peripheral nervous system

a)      Neurohumoral transmission

b)       Sympathetic nervous system – sympathomimetics, sympatholytics

c)       Parasympathetic – Cholinergics, Anticholinergics, Ganglion stimulants and blockers

d)       Skeletal muscle relaxants

e)       Local anaesthetics

(C)  Central nervous system

a)       General principles – neurotransmitters, definition and common transmitters

b)       Drug therapy of various CNS disorders like epilepsy, depression, Parkinson’s disease, schizophrenia, neuro- degeneration etc.

c ) Pharmacotherapy of pain

d)       General anaethetics

e)       Drugs for arthritides & gout

(D) Autacoids

a)       Histamine and antihistaminics

b)       Prostaglandins, leukotrienes, thromboxane and PAF c ) Substance P, bradykinin

(E)  Cardiovascular system

a)       Drug therapy of hypertension, shock, angina, cardiac arrhythmias

b)       Renin angiotensin system c ) Diuretics

d)       Coagulants and anticoagulants, antiplatelet drugs

e)       Hypo-lipidemics

(F)  Gastrointestinal and respiratory system

a)       Emetics and antiemetics

b)       Drugs for constipation and diarrhoea c ) Drug treatment of peptic ulcer

d)       Drug therapy of bronchial asthma

e)       Pharmacotherapy of cough

(G)         Hormones

a)       Reproductive hormones – testosterone, estrogen, progesterone, contraceptives

b)       Drug therapy of Diabetes c ) Thyroid hormones


d)       Pituitary-hypothalamic axis

e)       Corticosteroids

f)        Oxytocin and drugs acting on uterus

g)       Drugs affecting calcium balance

(H)  Chemotherapy


General principles of antimicrobial chemotherapy, rational use of antibiotics


Chemotherapeutic agents – Penicillins, cephalosporins, fluoroquinolones, macrolides, aminoglycoside, tetracyclines, chloramphericol and polypeptide antibiotics etc.


Chemotherapy of tuberculosis, leprosy, UTI


Chemotherapy of parasitic infection


Chemotherapy of fungal infections


Cancer Chemotherapy





Drug therapy of glaucoma and cataract


Treatment of poisoning

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