Pharmacology - I

Paul Ehrlich's concept that protozoal diseases could be cured by the administration of synthetic chemicals which selectively react with the target tissue of the protozoa rather than that of the host and Domagk's later expansion of this view to the treatment of bacterial diseases with the introduction of prontosil were the prominent landmarks in the birth of modern chemotherapy. The accuracy and the depth of clinical applications of these chemotherapeutic agents were further sharpened due to new inventions in the molecular biology which are increasingly involved to explain the mechanisms of action of many new chemotherapeutic agents. These broad area of pharmacology presented together with necessary data on the chemistry, absorption, excretion, tolerance and toxicity of the drugs are expected to provide a proper understanding of both, the value and limitations of the drug therapy.

1. Introduction to Pharmacology

2. Pharmacokinetic Aspects of Drug Action

3. Pharmacodynamics

4. Adverse Drug Reactions

5. Drug-Interactions

6. Drug Discovery and Clinical Evaluation of New Drugs

7. Neurohumoral Transmission

8. Parasympathomimetics and Parasympatholytics

9. Sympathomimetics and Sympatholytics

10. Neuromuscular Blockers

11. Local Anaesthetic Agents

12. Drugs used in Myasthenia Gravis and Glaucoma

13. Neuropharmacology

14. General Anaesthetic Agents

15. Sedative-Hypnotic Agents

16. Anti-Epileptics

17. Alcohols and Disulfiram

18. Psychopharmacological Agents

19. Drug Therapy in Parkinsonism and Alzheimer’s Disease

20. Central Nervous System Stimulants

21. Opioid Analgesics and Antagonists

22. Drug Dependence