UPTU Previous Question Papers
B Tech 8th Semester Protein Engineering 2006-07
Note : Attempt all questions.
All questions carry equal marks.
1 Briefly discuss the translation process of eukaryotic protein synthesis.
1 Explain the role of active sites in enzyme and effect of its confirmation change on reaction.
2 Discuss the effect of amino acid mutation on the tertiary structure of protein.
2 Discuss the protein structure stability in term of energy function.
3 Explain the Bragg’s law and its application for experimental structure determination of protein crystal.
3 Discuss the site directed mutagenesis as a tool for development of specific novel protein function.
4. Discuss the strategy for designing a new protein and its potential therpeutic application.
4 What are the properties of an enzyme that can be changed in newly designed protein?
5 Discuss the enzyme engineering of Tryesyl t RNA synthetase for its novel applications.
5 Discuss the enzyme engineering of Dihydrofolate reductase for its novel applications.