Gitam University Syllabus Pharmaceutical Biotechnology

Gitam University Syllabus

 Pharmaceutical Biotechnology


B.Tech. (BT) VI Semester
Course Code : EURBT 604 Category: CE

Batch reactors: introduction and overview of the subject, kinetics of homogeneous
reactions, nonelementary reactions; collision theory and transition-state theory,
arrhenius relation, various methods of analysis of batch reactor data (including
variable volume and variable pressure data). Isothermal batch reactor design.


Homogeneous flow reactors: design equation for plug flow reactor (PFR) and
continuous stirred tank reactor (CSTR), data analysis in flow reactors. Design of PFR
and CSTR. Cascade of CSTRs and combination of PFR and CSTR. (design of
autocatalytic reactions not included).

Multiple reactions: design for multiple reactions, parallel reactions, series reactions
(omit reversible and series-parallel reactions).


Non-isothermal design: energy balance equations for batch, PFR and CSTR under
non-isothermal conditions. Equilibrium conversion under adiabatic conditions.
Design of the homogeneous reactors under adiabatic conditions.
Non-ideal flow: residence time distribution curves E, F and C; interpretation of the
response data for the dispersion and tanks-in-series models (omit multiparameter


Heterogeneous catalysis: catalyst properties, physical adsorption and chemisorption,
adsorption isotherm, derivation of rate equations for various mechanisms (adsorption,
surface reaction and desorption controlling etc.) data analysis for heterogeneous
laboratory catalytic reactors. Isothermal packed bed (PFR) reactor design,
effectiveness factor and internal pore diffusion. Criteria for internal pore diffusion.


Text book:
1. Chemical reaction engineering. Levenspiel. 3rd edition. John Wiley. 1999
Reference books:
1. Elements of chemical reaction engineering. H.S.Fogler. 2nd editon. Prentice Hall,
2. Chemical engineering kinetics. J.M.Smith. 3rd edition. McGraw Hill. 1981

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