GITAM University Syllabus BE 8th Sem Modelling and simulation in Bioprocesses

GITAM University

Modelling and simulation in Bioprocesses

Syllabus VIII th Semester


B.Tech. (BT) VIII Semester

EURBT 842: Departmental Elective: Modelling and simulation in Bioprocesses
Code: EURBT 842 Category: DE
Credits: 3 Hours : 3 per week

Introduction to Bioprocesses, Modeling and Assessment in Process Development,
Development of Bioprocesses, Types of Bioprocesses and Bioproducts, Bioreaction
Stoichiometry, Thermodynamics and Kinetics, Elements of Bioprocesses, The
Development Process.
Modeling and Simulation of Bioprocesses: Problem Structuring, Process Analysis
and Process Scheme. Modelling Fundamentals, Formulation of Dynamic Models,
Implementation and Simulation, Uncertainty Analysis.
Sustainability Assessment. Sustainability, Economic Assessment, Environmental
Assessment, Assessing Social Aspects, Interactions Between the Sustainability
Bioprocess Case Studies.
Citric Acid – Alternative Process Using Starch , Introduction, Fermentation Model,
Process Model, . Inventory Analysis, Environmental Assessment, Economic
Assessment and Conclusions.
L-Lysine – Coupling of Bioreaction and Process Model, Introduction, Basic Strategy,
Bioreaction Model, Process Model, Coupling of Bioreaction and Process Model,
Results and Discussion.
Penicillin V. Introduction. Modeling Base Case. Inventory Analysis. Environmental
Assessment. Economic Assessment. Monte Carlo Simulations Conclusions.
Recombinant Human Serum Albumin. Introduction Bioreaction Model. Process
Model . Economic Assessment. Ecological Assessment. Conclusions.
?-1-Antitrypsin from Transgenic Plant Cell Suspension Cultures. Introduction.
Process Description. . Model Description. Discussion. Conclusions.
Text Books:
Chemical Engineering Dynamics: An Introduction to Modelling and Computer
Simulation, Third, Completely Revised Edition John Ingham, Irving J. Dunn, Elmar
Heinzle, Jiri E. Prenosil, Jonathan B. Snape (2007)
Development of Sustainable Bioprocesses: Modeling and Assessment,
Elmar Heinzle, Arno P. Biwer, Charles L. Cooney (2007)
Biological Reaction Engineering: Dynamic Modelling Fundamentals with Simulation
Examples, 2nd, Completely Revised Edition
Irving J. Dunn, Elmar Heinzle, John Ingham, Jiri E. Prenosil (2003)

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