GITAM University III SEM Biochemistry Syllabus

GITAM University III SEM Biochemistry Syllabus

 B.Tech. (BT) III Semester
BIOCHEMISTRY
Course Code : EURBT302 Category : BS
Credits: 3 Hours : 3 per week
UNIT-I
Organization of Life, Importance of Water in living Cell, Chemistry, Structure and
functions of Amino acids; Peptides: Solution and solid phase synthesis of peptides;
Proteins: classification, purification and physicochemical characterization. Protein
structure: Primary, secondary, tertiary and quaternary structure of proteins. Folding
and functions of Hemoglobin, Myoglobin, and Chymotrypsin. Enzymes:
classification, factors effecting enzyme action, Coenzymes.
UNIT-II
Carbohydrates: Classification structure and functions of: monosaccharide (ribose,
glucose, fructose), disaccharides (Sucrose and lactose), polysaccharides (starch,
cellulose and glycogen), Energetics of metabolic pathways, Glycogenesis and
glycogenolysis, glycolysis and TCA cycle, HMP shunt pathway, Electron transport
chain and oxidative phosphorylation. Energy coupling.
UNIT-III
Lipids: Classification, structure and physiological functions of triglycerides, fatty
acids, phospholipids, cerebrosides, gangliosides and cholesterol. Digestion and
absorption of fats. Synthesis and degradation of fatty acids and triglycerides.
UNIT-IV
Nucleic acids: Structure, properties and functions of purines pyrimidines, nucleotides
and nucleic acids. Cellular localization, isolation and estimation of nucleic acids,
Types of DNA and RNA. Biosynthesis and degradation of purine and pyrimidine
nucleotides, Oligonucleotide synthesis
UNIT-V
Biosynthesis and degradation of Heme. Physiological functions of vitamins and
minerals, hormones, Nutritional aspects of amino acids, protein and fatty acids.
Text Books:
1) Principles of Biochemistry by A.L.Lehninger, Nelson and Cox., CBS
Publications
2) Biochemistry by L.Stryer 6th Ed. 2006 (Freeman-Toppan)
3) Biochemistry by D.Voet and J.G.Voet. 2004 3rd ed. (John Wiley)
Reference:
1) Text Book of Biochemistry by West and Todd., (Mac Milan)
2) Essentials of Biochemistry by U. Satyanarayana. and Chekrapani. 2nd ed. 2005.
Allied publishers.
3) Harper’s Biochemistry 25th ed. 2000 McGrawHill.
4) Lehninger’s principles of biochemistry. Nelson and Cox. 2007. 4th ed.

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