Chromosomes To Genome

By Rakesh K. Mishra more
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Product Specifications

Publisher IK International All Biotechnology books by IK International
ISBN 9789380026213
Author: Rakesh K. Mishra
Number of Pages 224
Available in all digital devices
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Chromosomes To Genome by Rakesh K. Mishra
Book Summary:

Increasing number of complete genome sequences in the past decade has enhanced our understanding of chromosomal basis of genetic inheritance to molecular level. Chromosomes to Genome presents the historical perspective as well as the current state of this journey from chromosomes to genome.
The book presents complex topics in a simplified manner that is accessible to any student of biology. Each chapter provides a historical account of the field and reviews the recent work in this area, puts the subject in appropriate perspective and makes reading enjoyable. The book provides ‘genomic account’ of evolutionary history of emergence of complexity from simple living systems. It also gives glimpses of intricate regulatory mechanisms that act on genomic information during differentiation of different cell types.
Each chapter is written by well-known practising scientists leading very active and competitive groups engaged in unravelling the secrets hidden in the complex trail of DNA double helix in the immensely dense forest of eukaryotic nucleus.

Audience of the Book :
The book presents complex topics in a simplified manner that is accessible to any student of biology.
Key Features:

The main features of the book are as follows:

1.The book deals with the milestone discoveries and advancements in the quest for unravelling genomics from chromosomal studies.

2.The chapters are contributed by eminent scientists from India, the USA, the UK and Germany.

3. A variety of colour diagrams and photomicrographs have been included to aid the understanding of the concepts.

Table of Contents:

1. Snake’s Eye-view of Adam and Eve: From Chromosomes to Genome

2. The Neglected Parts of the Genome: Half a Century of Satellite DNA

3. Genome to Epigenome

4. Coordinated Demethylation and Methylation of Histones Controls Heterochromatin formation and gene silencing in Drosophila

5. Regulation of Higher Order Chromatin Organization and Function

6. Azoosperima factor (AZF) genes function for human male fertility

7. Hormonal signaling via nuclear receptors

8. Genomics of human sarcomas

9. Telomere dynamics in aging and cancer

10. Genetic basis of tropical calcific pancreatitis: Similar finds, different minds

11. Human genetic variations in India: Origin and disease perspectives

12. Heterochromatin on human Y-chromosome reveals new paradigms in regulation of gene expression in eukaryotes

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